Bottom Line Up Front:
Kingpin and Red Mags can handle most of these fights.
If you bring Kitty (Moleman and Zemo fights) and can bring Tigra for the fights then it's a lot easier.
Fight 1: VenomPool (Cosmic)
Fight 2: Moleman (Skill)
Fight 3: Red Hulk (Science)
Fight 4: Baron Zemo (Skill)
Ebb & Flow - Intercept: He has Protection. You can take it down by Intercepting him. You also get a Fury Passive when you intercept for 12 seconds. After the Fury expires the Protection returns and all Debuffs on him are Purified.
Repeat Offender - Taunt: Landing the same type of Basic Attack in a row inflicts a Taunt on him for 3 seconds.
Enhanced Special 2: His SP2 does more damage and the first part is Unblockable.
Wavering Will - Intercept: You can't reduce his Ability Accuracy. intercepting him disables this for 10 seconds.
Stay Awhile and Listen (Passive): When you get Rooted you are also Special Locked for 3 seconds.
Fight 5: Iron man (Tech)
Attacker Special Burst Lock Down: When you launch a Special Iron man is inflicted with a Heal Block and an Armor Break Debuff for 5 seconds.
Enhanced Special 1: His SP1 does more damage and the first part is Unblockable.
Combo Up: His Combo Meter increases by 1 each second unless you Intercept him. Then it's paused for 10 seconds.
Obstinate Charge: He is Stun Immune on his first attack. This goes on cooldown for 8 seconds if you Parry him, but not on the original Parry- he will be Stun Immune for that.
The Walls Are Closing In: You get 10 Tactus Charges when the fight starts and a 30 second timer begins. Each second that either of you are backed against the wall it reduces the Tactus Charges by 1. If the Charges are not at 0 when the 30 seconds are up then you take Degen dealing 30% of your Max Health over 5 seconds. When the Timer expires, the 30 seconds starts over and the Tactus Charges are reset.
Fight 6: Gladiator (Cosmic)
No Hit-M...ercy (Buff): Each time you knock him down he gains a Cruelty Buff giving him extra Crit Damage for 10 seconds. While he has the Cruelty he can Crit into your Block.
Now You See Me: Every 8 Seconds you get a Falter for 3 seconds. The timer resets each time you land a hit.
Steady Perseverance: When he launches a Special Attack, he gets a Stun Immune Buff for 4 seconds plus 2 seconds for each of his Unique Buffs. This Buff is paused during his Special Attacks.
Debilitate: Any Debuff he puts on you has +100% duration.
Long Distance Infinity: When he is far away from you- his Cruelty, Unstoppable, Vigilance, and Indestructible Buffs are paused.